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UWO / PHYSIOL2130
2000
Muscles Module 5 Biological machines that utilize chemical energy from breakdown and metabolism of food to perform useful work 600+ muscles Perform 3 main functions Movement Heat production Body support, posture Skeletal Muscle Whole muscles made up of bundles of fasciculi Each fascicle made up of groups cells or fibres Each muscle cell --> bundles myofibrils Each myofibril contains thick and thin myofilaments Thin <-- protein actin with troponin and tropomyosin Thick <-- myosin protein -->
2400
Nerves Module 4 Excitable Cells - Can use resting potential to generate electrochemical impulse (action potential) --> Ex. nerve & muscle cells Action Potential--> rapid reversal of resting membrane Strong depolarization at axon hillock triggers of Na+ Na+ rushes in Membrane depolarizes to +35mV Na+ channels inactivate, K+ open K+ rushes out Membrane re-polarizes +35mV --> 7-0mV K+ rushes out hyper polar -90mV K+ closes channel, slowly back to 7-0mV Voltage Gated Na+ Channel V--> depolariza
3700
Physiology Module 1 --> study of function in living organisms --> mechanisms which they control internal environment --> explains physical & chemical factors of function and disease Homeostasis <-- maintenance of internal environment Internal environment <-- interstitial fluid & blood plasma External environment <-- outside body, contents digestive, respiratory & urogenital tracts --> maintains homeostasis via (+) & (-) feedback Negative Feedback Control Systems --> all of them contain same
